Overview
This observational study aims to evaluate ocular anatomical parameters in patients undergoing anterior segment surgery using swept-source optical coherence tomography (SS-OCT).
Anterior segment surgery, including procedures involving the cornea, lens, and other anterior eye structures, may be associated with changes in ocular anatomy. SS-OCT is a non-invasive imaging technique that provides detailed images of the anterior structures of the eye and allows quantitative assessment of ocular anatomical parameters.
Patients undergoing anterior segment surgery at Nanfang Hospital, Southern Medical University, will be included in this study. SS-OCT will be used to assess ocular anatomical parameters, and the collected measurements will be analyzed to characterize anatomical features and explore potential differences among patients undergoing different types of anterior segment surgery.
The findings of this study may improve understanding of ocular anatomical characteristics in patients undergoing anterior segment surgery and provide useful information for clinical assessment and surgical management.
Description
- Background The anatomical structures of the anterior segment of the eye play an important role in ocular function and the clinical management of patients undergoing anterior segment surgery. Accurate evaluation of ocular anatomical parameters may provide valuable information for understanding individual anatomical characteristics and supporting clinical assessment.
Swept-source optical coherence tomography (SS-OCT) is a non-invasive imaging technology that enables detailed visualization and quantitative assessment of anterior segment structures. It provides an opportunity to investigate ocular anatomical characteristics in patients undergoing anterior segment surgery. 2. Study Objectives This study aims to characterize ocular anatomical parameters in patients undergoing anterior segment surgery using SS-OCT. The study will examine the distribution and variation of these parameters and explore potential associations between ocular anatomical characteristics and relevant clinical factors. 3. Study Design and Methods This is a prospective observational study involving patients undergoing anterior segment surgery at Nanfang Hospital, Southern Medical University.
Ocular anatomical parameters will be assessed using SS-OCT. Relevant demographic and clinical information will also be collected to support the evaluation of anatomical characteristics. The collected data will be analyzed to describe the distribution of ocular anatomical parameters and investigate potential differences or associations across relevant patient characteristics.
The study is observational in nature. Surgical treatment decisions will be made according to routine clinical practice rather than assigned by the research protocol. 4. Expected Significance This study is expected to provide a better understanding of ocular anatomical characteristics in patients undergoing anterior segment surgery. The findings may contribute to the clinical application of SS-OCT and provide reference information for anatomical assessment and individualized clinical management.
Eligibility
Inclusion Criteria:
- Voluntary provision of written informed consent.
- 18≤Age≤90 years.
- Patients diagnosed by an ophthalmologist with cataract, primary angle-closure disease, or other anterior segment disorders requiring anterior segment surgery.
- Availability of complete or accessible preoperative and postoperative clinical records and ophthalmic examination data.
Exclusion Criteria:
- Follow-up duration of less than 3 months.
- Substantial missing ophthalmic examination or perioperative data that prevents the required study analyses.
- Inability to obtain valid anterior segment imaging data due to severe corneal opacity, poor ocular fixation, inadequate cooperation, or other related factors.
- Presence of severe ocular trauma, intraocular tumors, severe corneal disease, active intraocular inflammation, or other ocular conditions that may substantially affect anterior segment structural assessment.
- History of complex intraocular surgery that may significantly alter anterior segment anatomy and is considered unsuitable for inclusion by the investigator.
- Other conditions considered by the investigator to make the patient unsuitable for participation in the study.


