Overview
Tear fluid will be collected from patients diagnosed with ocular trauma at the University of Pittsburgh Medical Center to evaluate biomarkers.
Description
Prospective, controlled, single-site, clinical trial evaluating tear fluid biomarkers in patients diagnosed with eye trauma at the University of Pittsburgh.
Eligibility
Inclusion Criteria:
- Minimum age of 18 years.
- Diagnosis of visually significant cataract and scheduled for routine cataract surgery at UPMC with a clear corneal incision or
- scheduled for clinical repair of a full-thickness corneal laceration.
Exclusion Criteria:
- Prior history of full-thickness corneal laceration from trauma or from a surgical procedure
- Current diagnosis of glaucoma or use of ocular hypotensive drops or oral aqueous suppressants.
- Actively being treated for the diagnosis of dry eyes with a topical drop other than artificial tears.
- Actively taking oral or topical supplementation of Vitamin C.
- Scheduled for additional eye surgeries, combined with the routine cataract surgery.
- Surgical plan that would include incisions in the clear for cataract extraction.
- Inability to provide informed consent due to suspected head trauma, altered mental status, or other factors impairing decision-making capacity.
