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Reliability of Multiple-Repetition-Maximum Tests in Patients With Cardiovascular Disease or Risk Factors

Reliability of Multiple-Repetition-Maximum Tests in Patients With Cardiovascular Disease or Risk Factors

Recruiting
50 years and older
All
Phase N/A

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Overview

Exercise training is a cornerstone in the prevention and rehabilitation of cardiovascular disease. While research has primarily focused on endurance training, resistance training becomes more and more important. The gold standard to prescribe resistance training intensity or monitor longitudinal changes is the 1-Repetition-Maximum (1-RM) test. However, particularly for unexperienced individuals, this test may not be recommendable due to the high load and an increased risk of injuries. Alternatively, there are several published formulas to estimate the 1-RM based on a multiple-repetition-maximum (or repetition-to-failure) test. However, these formulas have been primarily tested in healthy individuals. Moreover, the reliability of the 1-RM estimation based on two tests with different submaximal weight is unknown. Therefore, the present study evaluates the agreement of the 1-RM estimation (based on different formulas) between two Multiple-RM tests with different weight in 50 patients with cardiovascular disease (heart failure, coronary heart disease, atrial fibrillation) or cardiovascular risk factors (type 2 diabetes, arterial hypertension).

Eligibility

Inclusion Criteria:

  • Age ≥ 50 years
  • At least one of the following cardiovascular diseases / risk factors:
  • Heart failure
  • Coronary heart disease
  • Atrial fibrillation
  • Arterial hypertension
  • Type 2 diabetes mellitus
  • Clinically stable for ≥ 4 weeks
  • Medical clearance to perform resistance training / strength testing
  • Signed written informed consent

Exclusion Criteria:

  • Pregnancy
  • Acute infection
  • Chronic joint inflammation
  • Knee, hip, ankle, wrist, elbow or shoulder pain
  • Known osteoporosis (T-value ≤ -2.5)
  • Uncontrolled hypertension (≥160 mmHG systolic / ≥100 mmHG diastolic)
  • Known cerebral or thoracic aneurysm

Study details
    Heart Failure
    Coronary Heart Disease (CHD)
    Atrial Fibrillation (AF)
    Diabetes Mellitus
    Arterial Hypertension

NCT06796582

Technical University of Munich

24 October 2026

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