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Postoperative Pain and Success of Single-Visit Root Canal Treatment Using Different Root Canal Sealers in Asymptomatic Teeth

Postoperative Pain and Success of Single-Visit Root Canal Treatment Using Different Root Canal Sealers in Asymptomatic Teeth

Recruiting
18-65 years
All
Phase N/A

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Overview

This study evaluates the postoperative pain and long-term clinical and radiographic success of single-visit primary root canal treatment in asymptomatic teeth with periapical lesions.

Description

A total of 200 patients will be evaluated and divided into four treatment groups according to the root canal filling material and technique: AH Plus with warm gutta-percha, AH Plus with the single-cone technique, TotalFill BC Sealer with the single-cone technique, and One-Fil with the single-cone technique. Postoperative pain will be assessed, while periapical healing will be evaluated clinically and radiographically using the Periapical Index (PAI) during follow-up visits extending from 1 month to 1 year. The study aims to compare different root canal sealers and obturation techniques and contribute to the understanding of their long-term treatment outcomes.

Eligibility

Inclusion Criteria:

  • Patients aged 18-65 years.
  • Patients classified as ASA Physical Status I or II according to the American Society of Anesthesiologists (ASA) classification:
  • Teeth that have not previously undergone root canal retreatment or surgical intervention.
  • Patients who are able to read and sign the informed consent form.
  • Patients who are physically and mentally able to tolerate the planned dental treatment.
  • Teeth treated in a single treatment session.

Exclusion Criteria:

  • Pregnant or lactating women.
  • Patients with chronic periodontal disease and/or a periodontal probing depth \>4 mm.
  • Symptomatic patients.
  • Patients who are unable to comply with the scheduled follow-up periods.
  • Patients who have used analgesics within 1 week or antibiotics within 1 month prior to treatment.
  • Teeth with root resorption.
  • Teeth with a vertical root fracture or a risk of vertical root fracture.
  • Teeth with incomplete root development.

Study details
    Single-visit
    Periapical Periodontitis

NCT07868315

Istanbul Medipol University Hospital

21 October 2026

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