Overview
This multicenter prospective observational registry will evaluate the clinical characteristics and treatment outcomes of adults with local complications of acute pancreatitis or postoperative pancreatic fistula. Data generated during routine clinical care, including patient characteristics, imaging findings, treatments, adverse events, recurrence, and clinical outcomes, will be collected. Treatment is determined by the treating physicians and is not assigned by the study protocol.
Description
Local complications of acute pancreatitis, including pancreatic and peripancreatic fluid collections, may require conservative management, endoscopic or percutaneous drainage, necrosectomy, or surgery. Similar fluid collections may occur after pancreatic surgery as a result of postoperative pancreatic fistula. Evidence regarding treatment selection, timing, and outcomes remains limited because individual centers encounter relatively few cases.
This prospective multicenter registry will collect clinical, laboratory, imaging, treatment, and outcome data generated during routine care. The primary objective is to evaluate clinical success within 180 days after enrollment. Secondary objectives include technical success, adverse events, additional interventions, recurrence, mortality, and healthcare utilization.
Exploratory analyses will evaluate patient, disease, imaging, and treatment factors associated with clinical outcomes. No diagnostic or therapeutic intervention is assigned by the study protocol.
Eligibility
Inclusion Criteria:
- Age 18 years or older.
- Diagnosed with a local complication of acute pancreatitis, including acute exacerbation of chronic pancreatitis, or postoperative pancreatic fistula requiring routine clinical management.
- Receiving inpatient or outpatient care at a participating institution.
Exclusion Criteria:
- Considered unsuitable for participation by the treating investigator.
- Declines participation through the opt-out process.
