Overview
In fibromyalgia, the increased central sensitization symptom burden can lead to a disruption in the individual's interoception and difficulties in managing symptoms. Additionally, impaired internal perception can also affect conditions such as pain severity, fatigue, sleep quality, and accompanying depression and anxiety in fibromyalgia patients. With this study, the relationship between central sensitization and interoceptive sensitivity in fibromyalgia will be examined, and the relationship of interoceptive sensitivity with issues such as sleep quality, pain severity, fatigue, anxiety, and depression in fibromyalgia patients will also be investigated.
Description
Fibromyalgia is characterized by a complex symptom profile that includes pain, fatigue, sleep disturbances, and psychological distress. Interoception refers to the perception and interpretation of internal bodily signals and may be relevant to how individuals with fibromyalgia experience their symptoms. Examining interoceptive sensitivity alongside central sensitization-related symptoms may help clarify the relationship between internal bodily perception and symptom burden.
This cross-sectional observational study aims to investigate the association between interoceptive sensitivity and central sensitization symptom severity in individuals with fibromyalgia. Additional objectives are to examine the associations of interoceptive sensitivity with pain severity, fatigue, sleep quality, anxiety, and depression. Participants will undergo assessments of these domains using standardized measures, and the relationships between assessment scores will be analyzed.
The study will explore whether differences in interoceptive sensitivity are associated with central sensitization symptom burden and other clinical features of fibromyalgia. The findings may support a more comprehensive understanding of symptom experience in fibromyalgia and provide a basis for future longitudinal and interventional research.
Eligibility
Inclusion Criteria:
- Women patients aged 18-65
- Diagnosed with fibromyalgia according to the 2016 ACR criteria
- Experiencing widespread pain for at least 3 months
- Having the cognitive ability to complete the scales
- Having read and signed the informed consent form (ICF)
Exclusion Criteria:
- Being under 18 or over 65 years old
- Pregnancy
- Active inflammatory rheumatic disease
- Neurological disease
- Malignancy
- Severe psychiatric disorder
- Serious systemic disease such as heart or kidney failure


