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Volution of Pulmonary Artery Dimensions in Tetralogy of Fallot

Volution of Pulmonary Artery Dimensions in Tetralogy of Fallot

Recruiting
18 years and younger
All
Phase N/A

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Overview

Tetralogy of Fallot is the most common cyanotic congenital heart disease. Management strategies vary between primary repair and staged approaches including palliative surgery. The development of pulmonary arteries is a key determinant in surgical decision-making.

This multicenter retrospective observational study aims to evaluate the evolution of pulmonary artery dimensions using the Nakata index at key stages of patient management (birth, palliative surgery, and complete repair). The goal is to assess its predictive value in optimizing surgical strategy and improving outcomes in patients with Tetralogy of Fallot or pulmonary atresia with ventricular septal defect.

Eligibility

Inclusion Criteria:

  • Patients aged from birth to less than 18 years
  • Patients operated at Strasbourg or Bordeaux University Hospitals between 01/01/2010 and 31/12/2024
  • Patient (or legal guardians) not opposing the reuse of medical data for research purposes

Exclusion Criteria:

  • Patient expressing opposition to participation in the study
  • Parents/legal guardians or minor opposing data reuse
  • Specific clinical forms (VDDI)
  • Absence of subvalvular obstruction and absence of muscular resection

Study details
    Tetralogy of Fallot (TOF)
    Congenital Heart Defects

NCT07864129

University Hospital, Strasbourg, France

21 October 2026

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