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Study of General Foetal Movements Using Ultrasound

Study of General Foetal Movements Using Ultrasound

Recruiting
18 years and older
Female
Phase N/A

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Overview

This research explores General Movements (GMs) in a reference population. Abnormal general movements in babies are predictive of autism spectrum disorders or neurodevelopmental deficits.

General movements have received little attention in the context of foetuses, which is why developing a reading grid to analyse general movements in foetuses could be a valuable tool for facilitating early diagnosis and prompt treatment of at-risk babies.

Description

The identification of General Movements (GMs) in utero is not common practice among ultrasound technicians. However, it has been shown that poor or abnormal general movements in premature or full-term infants is a marker of the risk of later developing autism spectrum disorders or neurodevelopmental disorders. Prenatal screening currently focuses on detecting morphological malformations rather than the quality of general movements. Movement stimulates brain development through epigenetic action, and ultrasound enables this development to be monitored during pregnancy. General movements have been little studied in the foetus, and the introduction of a reading grid enabling general movements to be identified in utero could provide a new tool for ultrasound scanners in identifying risk situations at perinatal and/or postnatal level.

The investigators hypothesise that analysing ultrasound recordings as part of this research could lead to the creation of a grid to help identify general movements in utero. This would be a first step towards introducing a new tool for ultrasound technicians to use in the early detection of autism spectrum disorders or neurodevelopmental deficits.

Eligibility

Inclusion Criteria:

  • Patient aged over 18
  • Pregnant from 13 weeks of amenorrhoea
  • Indication for an ultrasound scan as part of the usual monitoring of her pregnancy
  • With no particular history or who has had a child with autism spectrum disorders or neurodevelopmental disorders
  • Able to understand the benefits and constraints of the research
  • Having given signed consent to participate, as well as that of his/her spouse.
  • Beneficiary of a social security scheme or entitled person (excluding AME).

Exclusion Criteria:

  • Pathological pregnancy
  • Under guardianship, curatorship or legal protection.

Study details
    Pregnant Woman
    Foetus Abnormal General Movements

NCT07868185

François FARGES

21 October 2026

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