Overview
This study aims to compare the 3-needle and 5-needle of genicular nerve block on pain and quality of life in Knee osteoarthritis (KOA).
Description
Knee osteoarthritis (KOA) is a common musculoskeletal disorder characterized by degeneration of articular cartilage and the subchondral bone. It leads to pain, stiffness, and functional decline in the affected knee joints.
Currently, the classical 3- nerve protocol targeting the superior medial, superior lateral, and inferior medial genicular nerves is the most commonly used technique for radiofrequency procedures.
Therefore, a five-needle Genicular nerve blocks (GNB) technique has been proposed to provide a more comprehensive blockade by targeting additional sensory branches.
Eligibility
Inclusion Criteria:
- Age ≥18 years.
- Both sexes.
- Patients with unilateral chronic knee pain for more than 3 months.
- Patients received conservative treatment for at least 3 months.
- Diagnosed Knee osteoarthritis (KOA) according to the American College of Rheumatology (ACR) criteria, and grade greater than or equal to Kellgren-Lawrence grade 2.
Exclusion Criteria:
- Chronic knee pain is due to causes other than KOA, such as connective tissue diseases, lumbar radicular neuropathy (spondylolisthesis, spinal stenosis), or sciatic pain.
- Knee effusion.
- Neuro/psychiatric disorders.
- History of intra-articular injection in the prior 3 months.
- Prior knee surgery.
- Active systemic or local knee infections; anticoagulant use.


