Overview
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and the preliminary evidence of disease-modifying effect of BMS-986528 in participants with refractory, difficult-to-treat rheumatoid arthritis (RA).
Eligibility
Inclusion Criteria
\- Adult participants with rheumatoid arthritis (RA) who meet definition of difficult-to-treat.
Exclusion Criteria
- Juvenile arthritis or onset of inflammatory arthritis before age 18.
- Seronegative RA participants in whom polymyalgia rheumatica has not been ruled out.
- Active fibromyalgia with pain symptoms or signs that would interfere with joint assessment.
- Other protocol-defined Inclusion/Exclusion criteria apply.
