Overview
This study compares two methods of prescribing parenteral nutrition (PN) in adults with cancer who are unable to meet nutritional needs by oral or enteral intake.
Description
This is a single-center, randomized, open-label pilot study enrolling 50 adult oncology patients requiring PN (parenteral nutrition). Participants are randomized to weight-based dosing or indirect calorimetry-guided dosing. Outcomes include feasibility, acceptability, changes in PN prescription, adverse events, quality of life, and survival.
Eligibility
Inclusion Criteria:
- Adults aged ≥18 years
- Diagnosis of cancer
- Requirement for PN ≥1 week
- Ability to provide informed consent
- English-speaking
Exclusion Criteria:
- Hospice enrollment
- Mechanical ventilation
- Chest tube or drain
- Continuous renal replacement therapy
- Supplemental oxygen


