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Prospective Case Series Evaluating 6-Month and 12-Month Outcomes After Cryoneurolysis for Chronic Pain

Prospective Case Series Evaluating 6-Month and 12-Month Outcomes After Cryoneurolysis for Chronic Pain

Recruiting
18 years and older
All
Phase N/A

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Overview

To prospectively describe patient-centered and health utilization outcomes through 12 months after cryoneurolysis performed as routine clinical care for chronic pain at Yale.

Eligibility

Inclusion Criteria:

  • Diagnosis of chronic pain (generally pain duration of at least 3-6 months) localized to an anatomical region appropriate for cryoneurolysis as determined by the treating physician.
  • Planned cryoneurolysis procedure as part of standard clinical care.
  • Ability to provide written informed consent.
  • Ability and willingness to complete baseline and follow-up questionnaires.

Exclusion Criteria:

  • Cryoneurolysis performed as part of a separate investigational trial in which data sharing is not permitted.
  • Active infection or other clinical contraindication to the procedure as determined by the treating clinician.
  • Life expectancy of less than 12 months in the judgment of the treating clinician.
  • Any condition that, in the investigator's opinion, would interfere with study participation or completion of follow-up, such as severe psychiatric instability or active substance use that precludes reliable follow-up

Study details
    Chronic Pain
    PERIPHERAL NEUROPATHY
    Occipital Neuralgia
    Chronic Hip Pain
    Hip Osteoarthritis
    Knee Osteoarthritis
    Spasticity
    Chronic Low Back Pain
    Lumbar Spondylosis
    Cervical Spondylosis
    Shoulder Arthritis
    Causalgia
    Chronic Pain Syndrome
    Chronic Neck Pain

NCT07639060

Yale University

22 August 2026

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