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CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)

CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)

Recruiting
60 years and older
All
Phase N/A

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Overview

The purpose of this multi-center clinical trial is to study the efficacy and safety of providing nutritional support added to the study-defined standard of care which consists of standardized dietary education and a single dietary counseling session shortly after discharge, versus study-defined standard of care alone.

Eligibility

Inclusion Criteria:

  • Veterans enrolled in a VHA facility
  • Hospitalized ( 24 hours) with new HF or worsening chronic HF
  • Dentition, swallowing function, etc. sufficient to safely consume food and liquid of standard composition and texture (i.e., no pureed food, no thickened liquids needed)
  • Able and willing to provide informed consent and perform study activities

Exclusion Criteria:

  • Food allergies or intolerances that cannot be accommodated by study diet
  • On dialysis or estimated glomerular filtration rate \<30 at randomization
  • Serum potassium (non-hemolyzed) \>6.0 mmol/L during index hospitalization
  • Heart transplant or active transplant listing
  • Left ventricular assist device present or anticipated \<6 months
  • Malignancy or other non-cardiac condition limiting life expectancy to \<12 months
  • Planned admission to a skilled nursing facility following hospital discharge, or discharge to other location/situation where Veteran does not have control over diet
  • Lack of space to store food for a week or equipment to prepare food
  • Severe cognitive impairment (SLUMS score \<20, or \<19 if less than high school education completed)
  • Severe food insecurity (5 or 6 points on the USDA 6-item Food Insecurity Screen)
  • Body mass index \>50 kg/m2
  • Other medical, psychiatric, behavioral, or logistical condition which, in the clinical judgement of the site investigator, makes it unlikely the patient can effectively participate in or complete the study

Study details
    Heart Failure

NCT05996328

VA Office of Research and Development

8 August 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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