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Impact of Non-surgical Periodontal Treatment on Targeted Metabolomics

Impact of Non-surgical Periodontal Treatment on Targeted Metabolomics

Recruiting
18-70 years
All
Phase N/A
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Overview

A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment by means of minimally invasive approach MINST or Q-SI (quadrantwise) approach in subjects with periodontitis on targeted metabolomics in gingival crevicular fluid

Description

A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment in subjects with periodontitis.

All the 60 patients with periodontitis are assessed for clinical, periodontal, and gingival crevicular fluid following of minimally invasive approach MINST or Q-SI (quadrantwise).

Measurements are taken before and after initial periodontal treatment in the periodontal subjects.

Eligibility

Inclusion Criteria:

  • Diagnosis of Periodontitis

Exclusion Criteria:

  • Periodontal treatment during the last 6 months
  • Use of antibiotics, NSAIDs, and immunosuppressants during the last 6 months
  • Pregnancy

Study details
    Periodontitis

NCT07740447

University of Catania

1 August 2026

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