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Low Dose Radiotherapy for Osteoarthritis

Low Dose Radiotherapy for Osteoarthritis

Recruiting
18 years and older
All
Phase N/A

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Overview

This single institution, multi-site, single arm prospective study will enroll patients with a history of OA and assess changes in pain and function after treatment with LDRT as measured by patient-reported outcomes.

Description

To evaluate the use of select instruments (BPI-SF, LEFS, UEFI, PROMIS Global) to detect changes in pain, function, and well-being in patients with OA who are refractory to or otherwise unable to receive other standard of care therapies.

Eligibility

Inclusion Criteria:

  • 18 years or older
  • Diagnosis of OA \>3 months in hips, knees, hands, shoulders, ankles or elbows.
  • Refractory to standard of care therapies for OA or those who are being considered for more aggressive interventional treatment such as joint replacement, but more conservative treatment is desired.
  • Provision of signed and dated informed consent.

Exclusion Criteria:

  • Unable to reasonably complete study instruments.

Study details
    Osteoarthitis

NCT07715188

Abramson Cancer Center at Penn Medicine

25 July 2026

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