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Prehab and Creatine/Whey Supplementation in Frailty Among Patients With Cirrhosis

Prehab and Creatine/Whey Supplementation in Frailty Among Patients With Cirrhosis

Recruiting
18 years and older
All
Phase N/A

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Overview

Frailty and muscle health are important for patients with chronic liver disease. This study looks at the use of a digital prehabilitation app (HEAL-ME) plus creatine and whey protein combination supplementation on maintaining muscle health in patients with liver disease. The investigators anticipate that this combination of supplementation and nutrition/exercise prehabilitation app will maintain muscle health in patients with liver disease.

Eligibility

Inclusion Criteria:

  • Confirmed diagnosis of cirrhosis by ICD-10 code, liver biopsy, abdominal imaging, or transient elastography
  • Access to digital device and internet at home
  • Ability to provide written informed consent before any study-related activities
  • Ability to remain in study for at least 3 months

Exclusion Criteria:

  • Allergy to milk protein
  • On hemodialysis
  • No English language proficiency
  • Presence of condition or abnormality that in opinion of the Investigator will compromise safety of the patient or quality of the data
  • Concomitant severe underlying systemic illness that in the opinion of the Investigator would interfere with completion of study
  • Pregnant, breastfeeding, or intention of becoming pregnant during study time frame

Study details
    Cirrhosis
    Frailty
    Sarcopenia

NCT07029243

University of California, San Francisco

18 July 2026

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