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A Real-World Study of Long-Term Adherence and Persistence to Inclisiran, Evolocumab, and Alirocumab

A Real-World Study of Long-Term Adherence and Persistence to Inclisiran, Evolocumab, and Alirocumab

Recruiting
18-99 years
All
Phase N/A

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Overview

This study aims to evaluate the long-term adherence and persistence to inclisiran and anti-proprotein convertase subtilisin/kexin type 9 (PCSK9) monoclonal antibodies (mAbs) in real-world clinical practice.

Eligibility

Inclusion criteria:

  • A first ever prescription of injection of inclisiran, evolocumab, or alirocumab during the identification period.
  • Age ≥18 years at index date.
  • With at least 12 months data availability prior to index date.

Exclusion criteria:

• Patients who received either evolocumab or alirocumab as their index study drug and who were dispensed the other anti-PCSK9-mAb (alirocumab and evolocumab respectively) before the identification period.

Study details
    Cardiovascular Diseases
    Atherosclerotic Cardiovascular Disease
    Hypercholesterolemia
    Familial

NCT07543731

Novartis Pharmaceuticals

18 July 2026

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