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Prospective Comparative Study of Clinical Outcomes and Complications in Medial Knee Prostheses: Fixed Bearing Versus Mobile Bearing Design

Prospective Comparative Study of Clinical Outcomes and Complications in Medial Knee Prostheses: Fixed Bearing Versus Mobile Bearing Design

Recruiting
50-80 years
All
Phase N/A

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Overview

This prospective study aims to systematically compare the clinical and radiological outcomes and complications of mobile versus fixed unicompartimental knee prostheses.

Description

In knee surgery, two dominant designs exist for the medial unicompartmental knee prosthesis (UKP): the fixed bearing (FB) and mobile bearing (MB) designs. The FB design is technically simpler to implant but has shown higher rates of early polyethylene wear in some studies. MB implants theoretically offer advantages in joint kinematics and load distribution but carry a risk of insert dislocation and periprosthetic fractures. An additional advantage of MB implants is the possibility of cementless implantation, potentially avoiding cement-related complications and reducing operative time.

Eligibility

Inclusion Criteria:

  • Age between 50 and 80 years
  • Indication for medial UKP
  • Intact anterior cruciate ligament
  • Good bone quality based on imaging
  • ASA score ≤ 3

Exclusion Criteria:

  • Inflammatory joint diseases
  • Collateral ligament instability
  • Simultaneous bilateral procedure
  • BMI \> 35
  • History of fracture or osteotomy in the knee joint
  • Neuromuscular diseases
  • Oncological indications

Study details
    Medial Gonarthrosis

NCT07677722

Jan Yperman Hospital

4 July 2026

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