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Using Text Messages to Improve Oral Chemotherapy for Adolescents and Adults With Acute Lymphoblastic Leukemia

Using Text Messages to Improve Oral Chemotherapy for Adolescents and Adults With Acute Lymphoblastic Leukemia

Recruiting
15-39 years
All
Phase N/A

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Overview

The purpose of this section is to learn how text message reminders might help with regularly taking chemotherapy medications for Adolescents and Adults with Acute Lymphoblastic leukemia (ALL).

Description

This study aims to compare adherence to oral mercaptopurine and methotrexate during the first 84-day cycle of maintenance therapy for adolescent and young adult patients with Acute Lymphoblastic Leukemia on pediatric-based regimens between those who receive the high intensity text message intervention and those who receive standard-of-care. It is believed that high-intensity text messages will increase patient adherence within cycle 1.

Eligibility

Inclusion Criteria:

  • Age of 15-39 years-old at the time of initial ALL diagnosis
  • Diagnosed with ALL
  • Currently receiving treatment with pediatric-based regimen that includes maintenance with mercaptopurine and methotrexate (e.g., CALGB 10403). Study participation begins with the start of maintenance, so enrollment occurs prior to the start of maintenance.

Exclusion Criteria:

  • Patient or caregiver who would receive text message reminders does not have a cell phone that receives text messages
  • Patient does not wish to participate
  • Text messages will be crafted in the patient's preferred language for medical communication, so English fluency is not an enrollment requirement.

Study details
    Acute Lymphoblastic Leukemia

NCT06446661

University of Chicago

27 June 2026

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