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Development and Validation of a Risk Prediction Model for De Novo Stress Urinary Incontinence After Pelvic Floor Reconstruction Surgery

Development and Validation of a Risk Prediction Model for De Novo Stress Urinary Incontinence After Pelvic Floor Reconstruction Surgery

Recruiting
20-90 years
Female
Phase N/A

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Overview

This observational study aims to develop a predictive model for the occurrence of new-onset stress urinary incontinence (SUI) after pelvic organ prolapse (POP) repair surgery in women. The primary questions it seeks to answer are:

Which risk factors and anatomical characteristics predispose women to new-onset stress urinary incontinence following pelvic organ prolapse repair surgery?

Female POP patients without any preoperative symptoms of urinary incontinence will receive telephone follow-ups at 3, 6, and 12 months after undergoing standard surgical treatment.

Eligibility

Inclusion Criteria:

  1. Patients with pelvic organ prolapse quantification (POP-Q) stage II or higher;
  2. Patients who require surgical treatment for pelvic organ prolapse;
  3. Patients with no evidence of urinary incontinence before surgery.

Exclusion Criteria:

  1. Patients confirmed to have urinary incontinence before surgery;
  2. Patients with urinary or reproductive system infections;
  3. Patients with a history of prior surgery for urinary incontinence;
  4. Patients who have undergone previous mesh repair surgery for pelvic organ prolapse;
  5. Patients with a history of psychiatric disorders, hearing impairment, or communication difficulties;
  6. Patients receiving hormone replacement therapy;
  7. Patients with neurodegenerative diseases such as stroke or multiple sclerosis, or neurological conditions such as spinal cord injury.

Study details
    Pelvic Organ Prolapse (POP)
    Stress Urinary Incontinence (SUI)

NCT07601282

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

27 June 2026

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