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Erythropoietin Gel Effect on Dental Implant Stability

Erythropoietin Gel Effect on Dental Implant Stability

Recruiting
20-50 years
All
Phase N/A

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Overview

  • Achieving and maintaining long-term osseointegration for dental implants is a key objective in the field of dentistry. The success of osseointegration is influenced by the surface treatment applied to dental implants. Numerous coating techniques have been developed to improve and speed up osseointegration.
  • The aim of the current study is to assess immediate dental implant stability coated with erythropoietin gel, both clinically and radiographically.
  • Materials and Methods: We conducted a randomized controlled clinical trial.The sample will include patients demanding immediate implant treatment in the anterior maxilla . Patients will be randomly allocated into the two groups of the study. The group A will be treated with erythropoietin gel coated dental implant immediately after extraction of non restorable teeth in the anterior maxilla . Group B will be treated with non coated dental implant immediately after extraction of non restorable teeth in the anterior maxilla .
  • The primary outcome variable will be implant stability and the secondary outcome will be crestal marginal bone level and bone density around implants. It will be measured at time of implant placement and reevaluated after 6-months .

Eligibility

Inclusion Criteria:

  • All patients Should have nonrestorable teeth in the anterior maxilla indicated for extraction and seeking implant placement.
  • Good general periodontal health and maintenance.

Exclusion Criteria:

  • Heavy smokers who smoke more than ten cigarettes per day
  • Acute infected socket
  • Ant socket with wall defect.
  • Pregnency
  • Local or systemic conditions that will interfere with bone healing (uncontrolled diabetes mellitus or human immune deficiency virus infections, resonance therapy), bone disorders (hyperparathyroidism, osteoporosis, or Paget's disease.
  • Patients who had subjected to intravenous and/or oral bisphosphonate therapy.

Study details
    Osseointegration

NCT06665451

Al-Azhar University

27 June 2026

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