Overview
The goal of this clinical trial is to learn if a treatment for adults with PTSD called prolonged exposure + incentives (PE+) works to treat pregnant patients. The main question it aims to answer is:
Does PE+ decrease PTSD symptoms?
All participants will receive PE+ to see if their PTSD symptoms at the end of the trial are less than at the beginning.
Participants will:
- Receive individual PE+ therapy for 1 hour weekly for 12 weeks.
- Receive financial incentives for attending each PE+ session.
- Attend assessment visits every 4 weeks for the 12 weeks of the trial.
- Allow research staff to collect some information about their labor and delivery from their medical records after their babies are born.
Eligibility
Inclusion Criteria:
- Female
- \>18 years old
- Gestational age ≤ 25 weeks
- Meet current DSM-5 posttraumatic stress disorder criteria based on the Clinician Administered PTSD Scale for DSM-5
- Participants receiving psychotropic medications must be maintained on a stable dose for \>14 days prior to enrollment.
Exclusion Criteria:
- Male
- Under 18 years old
- Gestational age \> 25 weeks
- No current diagnosis of PTSD
- Current delusions or hallucinations, unstable bipolar disorder, imminent risk for suicide as assessed by the Mini International Neuropsychiatric Interview
- Enrolled in another ongoing evidence-based treatment for PTSD.


