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A Study to Investigate the Clinical Outcome and Quality of Life in Chinese Post-operative CRSwNP Patients

A Study to Investigate the Clinical Outcome and Quality of Life in Chinese Post-operative CRSwNP Patients

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Overview

This is a prospective, multicenter real-world study to describe the postoperative outcomes and quality of life, disease control and characteristics of patients who underwent surgery, as well as economic burden and post-operative treatment patterns in Chinese patients with CRSwNP recurrence.

Description

This is a prospective, multicenter real-world study to describe the postoperative outcomes and quality of life, disease control and characteristics of patients who underwent surgery, as well as economic burden and post-operative treatment patterns in Chinese patients with CRSwNP. Patients will receive standard medical care as determined by the treating physician at each site and undergo scheduled clinical assessments.

Approximately 200 patients diagnosed with CRSwNP by physicians and scheduled for surgical treatment will be enrolled across 20 centres in different regions of China.

Eligibility

Inclusion Criteria:

  1. Participant must be 16 years of age or older, at the time of signing the informed consent.
  2. Participants with a documented diagnosis of CRSwNP.
  3. Endoscopic nasal polypectomy is performed during the screening period.
  4. Voluntarily participate and sign the informed consent form as described in A 3.
  5. No history or current psychiatric disorders, with normal cognitive functions including understanding, expression, and orientation.

Exclusion Criteria:

  1. Any significant disease or disorder that the investigator believes may place the patient at risk or may affect the study results or the patient's ability to participate in the study.
  2. Currently participating in an interventional study.
  3. Patients who are unable to independently complete questionnaires due to language barriers or mental status.

Study details
    Chronic Rhinosinusitis With Nasal Polyps

NCT07446738

AstraZeneca

13 May 2026

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