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LiverSleep: A Behavioral Sleep Intervention for Patients With Cirrhosis and Insomnia

LiverSleep: A Behavioral Sleep Intervention for Patients With Cirrhosis and Insomnia

Recruiting
18 years and older
All
Phase N/A

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Overview

This is a pilot trial to test the feasibility and acceptability of a virtual cognitive behavioral program for insomnia for patients with cirrhosis.

Eligibility

Inclusion Criteria:

  1. Adult (≥ 18 years) patients with cirrhosis (either compensated or decompensated) receiving ambulatory care at the MGH Liver Clinic or MGH Liver Transplant Evaluation Clinic
  2. Have the ability to communicate in English
  3. Have at least mild insomnia (ISI score ≥8) and report sleep difficulty, defined as ≥ 30 min to fall asleep or spending at least 30 min awake during the night

Exclusion Criteria:

  1. Uncontrolled neuropsychiatric disorders such as severe depression, schizophrenia, or suicidal ideation which prohibits their ability to provide informed consent.
  2. Cognitive impairment, which we will screen for using the simplified Animal Naming Test
  3. Current alcohol misuse
  4. Diagnosis of obstructive sleep apnea that is untreated or high-risk for obstructive sleep apnea
  5. Severe restless leg syndrome
  6. Those with night/rotating shift work

Study details
    Cirrhosis
    Insomnia

NCT07417163

Massachusetts General Hospital

13 May 2026

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