Overview
The purpose of this study is to determine the safety and efficacy of Injectrode Tibial Nerve Stimulation for bladder function in people with spinal cord injury.
Eligibility
Inclusion Criteria:
- Non-progressive chronic (\>1 year) SCI
- Neurologic level of injury T9 and above
- Stable over active bladder (OAB) medications (≥3 months)
- No contraindication to MRI (per MRI Safety Questionnaire)
- English or Spanish speaking
- Tolerate and be able to evoke toe flexion bilaterally with transcutaneous tibial nerve stimulation (tTNS) (self or assisted)
- Pass the tTNS competency checklist to perform or direct performance of tTNS.
Exclusion Criteria:
- Ongoing/active genitourinary oncologic diagnoses
- History of other central nervous system disorder (CNS) disorders and/or peripheral neuropathy
- Pregnancy or planning to become pregnant.
- Lower Motor Neuron bladder
- Restorative bladder surgery such as augmentation cystoplasty
- Botulinum toxin-A injections in the bladder within 6 months of trial enrolment (injection in other sites is allowed)
- Anticoagulation treatment or prophylaxis
- Advanced peripheral vascular disease (gangrene, amputation, etc.)
- History of intolerance to electrical stimulation, particularly of the leg
