Image

Comparison of the Effects of Sevoflurane and Desflurane on Optic Nerve Sheath Diameter During Laparoscopic Surgery

Comparison of the Effects of Sevoflurane and Desflurane on Optic Nerve Sheath Diameter During Laparoscopic Surgery

Recruiting
18-85 years
Female
Phase N/A

Powered by AI

Overview

Laparoscopic surgeries require pneumoperitoneum and Trendelenburg position, which may lead to increased intracranial pressure (ICP).

Optic nerve sheath diameter (ONSD) measurement via ultrasound is a non-invasive method to evaluate ICP.

This prospective study aims to compare the effects of sevoflurane and desflurane on ONSD in patients undergoing laparoscopic hysterectomy and bilateral oophorectomy in the Trendelenburg position.

Description

The primary objective of this study is to compare the ONSD values measured by ultrasound between the sevoflurane and desflurane groups.

The secondary objective is to evaluate the relationship between ONSD changes, hemodynamic parameters, and postoperative neurological complications.

Eligibility

Inclusion Criteria:

  • Patients planned for laparoscopic hysterectomy bilateral oophorectomy surgery under general anesthesia.

Exclusion Criteria:

  • Patients receiving beta-blocker or diuretic treatment.
  • Patients with severe heart failure.
  • Patients diagnosed with diabetes with ocular or neurological complications.
  • Patients who have undergone cardiac surgery, eye surgery, brain surgery, or thoracic surgery.
  • Patients with a history of hydrocephalus, glaucoma, intracranial mass, and stroke.

Study details
    Intracranial Pressure
    Laparoscopic Surgery
    Optic Nerve Sheath Diameter

NCT07525648

Medipol University

13 May 2026

Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.