Overview
The goal of this observational study is to learn how a perioral rejuvenation procedure affects perioral line severity and lip volume over time in adults undergoing routine aesthetic treatment in a single clinical center. The main questions it aims to answer are:
- What proportion of participants achieves a ≥1-point improvement from baseline on both the Lip Fullness Scale (LFS) and the Static Perioral Lines Assessment Scale (SPLAS) at Week 12?
- How do skin wrinkling/surface roughness, lip and perioral volume, and patient satisfaction change over 6 and 12 weeks?
Participants will:
- Receive a routine (non-study-mandated) holistic perioral rejuvenation procedure as decided by their treating clinician.
- Attend study visits at approximately baseline, Week 6, and Week 12.
- Undergo independent clinical assessments (assessor not involved in treatment delivery) of LFS and SPLAS.
- Have skin wrinkling and surface roughness documented by VISIA skin analysis (baseline, Week 6, Week 12).
- Have lip and perioral volume measured by VECTRA M3 volume analysis (baseline, Week 6, Week 12).
- Complete a standardized patient satisfaction questionnaire (Week 12).
Eligibility
Inclusion Criteria:
- 18 years or older at time of treatment.
- At least mild static perioral lines and maximum of thin lips, as assessed by the investigator.
- Participant has a stable medical condition with no uncontrolled systemic disease.
- Willingness to participate in the routine follow-up after 12 weeks and a signed ICF.
- Participant already visiting the clinic for the specific treatment.
Exclusion Criteria:
- Pregnancy and breast feeding.
- Known impairment of blood coagulation.
- Presence of acute infection or inflammation at the proposed injection sites.
- Hyaluronic Acid-Filler treatment in the perioral area within the last 6 months.
- Patients with a history of autoimmune disease or who are receiving immune therapy.
- History of hypersensitivity to hyaluronic acid, lidocaine hydrochloride or other amidetype local anaesthetics.
