Overview

This study aims to compare the effects of combined intravenous-inhalational anesthesia versus inhalational anesthesia alone on postoperative recovery in patients undergoing elective gynecologic surgery.

A total of 100 patients, aged 18-65 years and classified as ASA I-III, scheduled for elective gynecologic procedures at Sakarya University Faculty of Medicine Training and Research Hospital, will be included. The sample size was calculated based on the primary outcome, the Quality of Recovery-15 (QoR-15) score.

Patients will complete the QoR-15 questionnaire preoperatively, before knowing which anesthesia method will be applied. Postoperative QoR-15 scores will be collected on postoperative days 1 and 2, and intraoperative data will be obtained from anesthesia records.

The study evaluates postoperative recovery using QoR-15 scores, covering physical comfort, emotional state, psychological support, pain, and ability to perform daily activities. Higher scores indicate better recovery, whereas lower scores indicate impaired postoperative recovery.

Eligibility

Inclusion Criteria:

1. Patients aged 18-65 years
2. Scheduled for elective gynecologic surgery at Sakarya University Faculty of Medicine Training and Research Hospital
3. Classified as ASA I-III
4. Able to understand and complete the QoR-15 questionnaire
5. Provided written informed consent

Exclusion Criteria:

1. Severe comorbidities (beyond ASA III)
2. Patients with advanced neurological disease or cognitive impairment
3. Known allergy to anesthetic drugs used in the study
4. Classified as ASA IV-V
5. Refusal to participate in the study
6. Emergency or urgent surgery