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A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris

A Phase 2/3 Study of Brepocitinib in Adults With Lichen Planopilaris

Recruiting
18 years and older
All
Phase 2/3
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Overview

This study will evaluate the clinical safety and efficacy of oral brepocitinib in participants with lichen planopilaris

Eligibility

Inclusion Criteria:

  1. Age ≥ 18 years
  2. Scalp biopsy consistent with LPP
  3. Active and symptomatic LPP at screening and baseline-
  4. Weight \> 40 kg to \< 130 kg with BMI ≤ 45 kg/m2

Exclusion Criteria:

  1. History of: Lymphoproliferative disorder; Active malignancy; History of cancer within 5 years prior to baseline (exceptions for basal cell carcinoma, squamous cell carcinoma, ductal carcinoma in situ of the breast, carcinoma in situ of the uterine cervix, or thyroid cancer).
  2. High risk of thrombosis or cardiovascular disease
  3. High risk of herpes zoster
  4. Active or recent infection

Study details
    Lichen Planopilaris

NCT07532603

Priovant Therapeutics, Inc.

13 May 2026

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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