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Targeting Neuroplasticity for Persistent Post-Concussive Cognitive Symptoms

Targeting Neuroplasticity for Persistent Post-Concussive Cognitive Symptoms

Recruiting
18-65 years
All
Phase N/A
  • Technical (Original)
  • Simplified (AI rewritten)

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Overview

This project investigates an innovative combination of non-invasive neuromodulation (transcranial direct current stimulation - tDCS) and cognitive training as a novel treatment approach aimed at improving function in individuals suffering from persistent post-concussive syndrome (PPCS) following mild traumatic brain injury (mTBI).

Eligibility

Inclusion Criteria:

  • Age 18-65
  • Has sustained a single mTBI 3-12 months prior to enrollment
  • Meets criteria for PPCS (assessed using the CP Screen)
  • Has reliable access to a smartphone

Exclusion Criteria:

  • Inability to provide informed consent or complete study procedures
  • History of moderate/severe TBI
  • Significant neurological or psychiatric disorders (other than PPCS-related symptoms like mild depression/anxiety)
  • Substance dependence within the last six months
  • Contraindications to tDCS (e.g., implanted metal, skin lesions on scalp)

Study details
    Persistent Post Concussion Syndrome
    Mild Traumatic Brain Injury

NCT07246993

University of Minnesota

13 May 2026

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