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Cannabis Reduction and Functional Outcomes

Cannabis Reduction and Functional Outcomes

Recruiting
18 years and older
All
Phase N/A
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Overview

This study evaluates the effects of cannabis use reduction among adults diagnosed with cannabis use disorder (CUD). Participants will undergo an 8-week intervention combining motivational interviewing, computerized cognitive behavioral therapy (CBT4CBT), and financial incentives for reduction in urinary cannabinoids. The study aims to assess improvements in cannabis-related problems, sleep, cognitive performance, CUD severity, and quality of life.

Eligibility

Inclusion Criteria:

  • Age 18+
  • Urinary cannabinoid level ≥ 50 ng/mL
  • DSM-5 diagnosis of CUD (mild, moderate, or severe)
  • Willingness to attempt cannabis reduction
  • Completion of Intake Visit

Exclusion Criteria:

  • Serious medical/psychiatric conditions
  • Pregnancy or breastfeeding
  • Use of cannabis in past 30 days was for medical purposes only
  • Discontinuation or reduction of cannabis use may exacerbate a pre-existing condition
  • Cognitive or understanding difficulties, as evidenced by inability to pass informed consent quiz

Study details
    Cannabis Use Disorder

NCT07218471

Medical University of South Carolina

13 May 2026

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FAQs

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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