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Using taVNS to Modulate Cardiovascular Function in Individuals With Neurologic Disease

Using taVNS to Modulate Cardiovascular Function in Individuals With Neurologic Disease

Recruiting
18-80 years
All
Phase N/A
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Overview

The purpose of this study is to find out whether a type of gentle nerve stimulation, called transcutaneous auricular Vagus Nerve Stimulation (taVNS), can help improve how the body regulates heart rate and blood pressure in people with Parkinson's Disease (PD). Problems with heart rate and blood pressure control are common and can make it harder for people to exercise or do daily activities. By using this non-invasive form of nerve stimulation and testing how it affects the body's natural responses, this study hopes to learn if taVNS could be a helpful tool to support physical therapy and improve overall function.

Eligibility

Inclusion Criteria:

  • Diagnosis of idiopathic PD
  • Stable medication for at least 4 weeks prior to the study

Exclusion Criteria:

  • Use of beta blockers
  • Sustained severe hypertension (\>/= 180/110 mmHg while seated)
  • Significant uncontrolled cardiac arrhythmia
  • Unstable angina
  • Congestive heart failure
  • History of myocardial infarction
  • History of seizures
  • Severe cognitive impairment
  • Pregnant women or women who are planning to become pregnant

Study details
    PARKINSON DISEASE (Disorder)

NCT07557706

University of Alabama at Birmingham

13 May 2026

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FAQs

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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