Overview
The aim of this study to evaluate pre-injection patient-related factors that may influence treatment response in patients with medication-overuse headache who underwent ultrasound-guided greater occipital nerve block.
Eligibility
Inclusion Criteria:
- Age between 18 and 65 years
- Diagnosis of medication-overuse headache according to the International Classification of Headache Disorders, 3rd edition (ICHD-3)
- Diagnosis of medication-overuse headache associated with the use of triptans or nonsteroidal anti-inflammatory drugs
- Previous diagnosis of chronic migraine or chronic tension-type headache according to the ICHD-3 criteria
Exclusion Criteria:
- History of severe head or neck trauma or previous neurosurgical intervention
- Presence of a severe psychiatric disorder (e.g., severe depression, schizophrenia)
- History of infectious disease, chronic inflammatory disease, or malignancy
- Previous diagnosis of secondary headache
- History of substance abuse
- Pregnancy or breastfeeding
- History of an additional neurological disorder (e.g., cerebrovascular disease, multiple sclerosis)
- Difficulty with cooperation
- Presence of a concomitant systemic disease that may affect quality of life (e.g., congestive heart failure, chronic kidney disease, chronic liver disease, pulmonary disease, uncontrolled diabetes, or peripheral vascular disease)
