Overview
The purpose of this study is to collect pancreas fluid from the duodenum using the endoscopic pancreas function collection method in healthy participants after pancreatic stimulation with human secretin.
Eligibility
Inclusion Criteria
- Males or non-pregnant females
- Age 18-80.
- Participants must be in good health based on medical history (ASA Class 3 or below)
- Participants must be willing and able to provide informed consent
- Receiving an endoscopic ultrasound for a non-pancreatic indication
Exclusion Criteria
- History of any form of pancreatitis and/or other pancreatic diseases (e.g. pancreatic cysts, pancreatic masses).
- History of inflammatory bowel disease
- History of vagotomy.
- History of surgically altered upper gastrointestinal anatomy (e.g. gastric bypass, Billroth I/II)
- History of liver disease
- Pregnant women or nursing mothers
- Regular use of anticholinergics
- \> 2 drinks of alcohol daily
- Smokers (cigarette)
