Overview
To evaluate the safety and tolerability of human umbilical cord mesenchymal stem cells combined with bovine type I collagen in the treatment of third-degree burn wounds.
Eligibility
Inclusion Criteria:
- Aged 18-65 years, gender unrestricted
- Confirmed third-degree burns, wound area 1%-5% TBSA
- Admission within 72 hours after burn injury
- Voluntarily signed informed consent
- Able to cooperate and complete follow-up
Exclusion Criteria:
- Pregnant or lactating females
- Severe immunodeficiency or autoimmune disease
- History of malignant tumor, or coagulation dysfunction
- Severe cardiac, hepatic, or renal insufficiency
- Hypersensitivity to collagen or stem cell components
- Uncontrollable severe wound infection
- Participation in other clinical studies within the past 3 months
- Inability to comply with follow-up


