Overview
Volunteers were divided into 2 groups: mulberry leaf extract capsule (DNJ 12mg) group and placebo group. They took the sample 3 times/day for 8 weeks. Complete blood count, Blood urea nitrogen (BUN), Creatinine, Aspartate transaminase (AST), Alanine aminotransferase (ALT), Alkaline phosphatase (ALP), Fasting plasma glucose, HbA1c, and adverse effects were evaluated before and after 4 and 8 weeks.
Description
Volunteers were divided into 2 groups: mulberry leaf extract capsule (DNJ 12mg) group and placebo group. They took the sample 3 times/day for 8 weeks. Complete blood count, Blood urea nitrogen (BUN), Creatinine, Aspartate transaminase (AST), Alanine aminotransferase (ALT), Alkaline phosphatase (ALP), Fasting plasma glucose, HbA1c, and adverse effects were evaluated before and after 4 and 8 weeks. Satisfaction was assessed after 8 weeks.
Eligibility
Inclusion Criteria:
- Male or female age more than 18 years
- No Diabetis mellitus disease and no taking diabetes medication
- Blood sugar level less than 126 mg/dl and HbA1C less than 6.5
- Can using Thai language
- Willing to participate in the study
Exclusion Criteria:
- Allergic to mulberry extract
- Take mulberry extract in 2 weeks before participate in this study
- Take medications that have effect on blood sugar level such as steroid in 2 weeks before participate in this study
- Have uncontrolled disease
- Have AST, ALT, ALP more than 3 times of normal value, or estimated Glomerular Filtration Rate less than 30 ml/min/1.73 m2)
- Pregnancy or lactation
