Overview
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ME3241 Administered Intravenously in Healthy Adult Participants
Eligibility
Inclusion Criteria:
- Participant must be 18 to 55 years of age, inclusive, at the time of signing the informed consent.
- Participant must be in good general health as determined by the investigator based on medical history, physical examination, vital signs, 12-lead electrocardiogram (ECG), and clinical laboratory tests.
- Participant must have body weight \> 45 kg at the Screening Visit.
- Participant must have a body mass index (BMI) between 18.0 and 30.0 kg/m\^2 at the Screening Visit. BMI = body weight (kg)/(height \[m\])\^2.
Exclusion Criteria:
- Participant with concurrent or history of potentially fatal infections such as opportunistic infections, including sepsis and systemic fungal infection.
- Participant with history of pulmonary infiltrates or pneumonia within 6 months prior to the Screening Visit.
- Participant with concurrent or history of autoimmune, cardiac, hepatic, renal, gastrointestinal, respiratory, endocrine, neurological, central nervous, mental disorders, and/or hematological function disorders, which, in the judgment of the investigator, may affect participation in this clinical study.
- Participant with history and/or presence of malignancy of any organ system (including basal cell carcinoma of the skin), treated or untreated.
Other protocol defined inclusion/exclusion criteria could apply.
