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A Study to See if an Energy Drink With Caffeine and Green Tea Increases Fat Burning When Exercising

A Study to See if an Energy Drink With Caffeine and Green Tea Increases Fat Burning When Exercising

Recruiting
18-45 years
All
Phase 4

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Overview

The goal of this study is to evaluate the influence of consuming a drink containing a combination of caffeine and green tea extracts on fat oxidation responses at rest, during and after a period of endurance type exercise.

Description

This study investigates whether consuming an energy drink containing caffeine and green tea extract before exercise increases fat burning (oxidation) compared with a placebo drink. Healthy, moderately active adults will attend three visits at clinic over 3-5 weeks. The first visit determines each participant's individual exercise intensity that maximises fat use during cycling. At two subsequent visits, participants will consume either the active drink or a placebo before completing a 30-minute cycling session at their personalised intensity. Fat and carbohydrate use, heart rate, blood pressure, and subjective responses will be measured at rest, during exercise, and after exercise using a double-blind, crossover design.

Eligibility

Inclusion Criteria:

  • Passing the Exercise and Sport Science Australia adult pre-exercise screening system (APSS) stage 1 \& 2 (see appendix 4).
  • Between the ages of 18 and 45,
  • Not sedentary, and not completing more than 150 minutes of low and/or moderate and/or or vigorous intensity endurance exercise a week,
  • Ability to commit to in principle fulfilment of all 3 trial visits,
  • No history of coagulopathy e.g., DVT, stroke,
  • No known heart disease,
  • No known pancreatic insufficiency,
  • No known inflammatory bowel disease, or prior bowel resection or bypass surgery (excluding gastric banding and sleeve),
  • BMI of 22.0 to 34.9 kg/m2,
  • No known allergies to caffeine or green tea extract,
  • No known type I or II diabetes,
  • No uncontrolled concurrent illness,
  • No known current pregnancy or breastfeeding women
  • No current regular consumption of supplements (\>2 times a week) or foods and drinks containing caffeine and/or green tea extracts (\>2 times per day, weekly).
  • Agree not to consume caffeine for 12-hours prior to the clinic visit.

Exclusion Criteria:

  • Triggering any of the exclusion screening criteria as outlined below, and in compliment with the Exercise and Sport Science Australia adult pre-exercise screening system (APSS).
  • Under the age of 18 or over the age of 45,
  • Sedentary, or completing over 150 minutes of low and/or moderate and/or or vigorous intensity endurance exercise a week,
  • Inability to commit to in principle fulfilment of all 3 trial visits,
  • History of coagulopathy e.g., DVT, stroke,
  • Known heart disease,
  • Known pancreatic insufficiency,
  • Known inflammatory bowel disease, or prior bowel resection or bypass surgery (excluding gastric banding and sleeve),
  • BMI \< 22.0 or \> 34.9 kg/m2,
  • Known allergies to caffeine or green tea extract,
  • Known type I or II diabetes,
  • Uncontrolled concurrent illness,
  • Taking GLP-1 agonists, caffeine, or any other medication known to affect metabolism.
  • Known current pregnancy or breastfeeding women.
  • Currently regularly consuming supplements, foods or drinks containing a caffeine and green tea extract blend, or not willing to abstain for the study

Study details
    Exercise

NCT07434752

RDC Clinical Pty Ltd

13 May 2026

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