Overview
This research is studying the use of a new type of standing desk in a small number of people to learn about the user experience for people with Parkinson's disease. 12 4-hour sessions will be performed to test the primary hypothesis that dynamic standing improves gait function compared to static standing and control sitting. This study has 2 phases. Phase 1 will be an open-label study and Phase 2 will be an in-lab randomized controlled trial pilot study. This is phase 1 of the study.
Description
For phase 1, participants will attend up to 12 4-hour sessions using the dynamic standing desk. In addition to these sessions, there will be a clinical assessment at baseline and an outcome session (endpoint assessments). In total, there will be up to 14 sessions per participant. All sessions need to be completed within 6 weeks. At the baseline session, clinical measurements will be collected. These measures will be repeated in the outcome session.
Eligibility
Inclusion Criteria:
- Diagnosis of Parkinson's Disease
Exclusion Criteria:
- Inability to stand or walk without an assistive device
- History of symptoms in stance that preclude safe and comfortable participation, such as dizziness and lightheadedness, orthostasis, severe symptomatic leg or back musculoskeletal pain, or medication side effects
- Any other history of medical or psychiatric comorbidity, precluding safe participation in the project.
- History of symptomatic cardiovascular or pulmonary disease
- History of active rheumatic arthritis
- History of stroke or other neurologic conditions with significant residual sensorimotor deficits
- History of disabling chronic pain syndrome requiring narcotic analgesics
- Evidence of dementia (Mini Mental State Exam (or Montreal Cognitive Assessment test) \<24 and significant impairment in activities of daily living)
- Venous ulcerative stasis or severe varicosities.
- Pregnancy as determined by urine pregnancy test prior to DXA procedure in women of childbearing potential.


