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A Pilot Study of In-lab Dynamic Standing in Parkinson's Disease

A Pilot Study of In-lab Dynamic Standing in Parkinson's Disease

Recruiting
50 years and older
All
Phase 1

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Overview

This research is studying the use of a new type of standing desk in a small number of people to learn about the user experience for people with Parkinson's disease. 12 4-hour sessions will be performed to test the primary hypothesis that dynamic standing improves gait function compared to static standing and control sitting. This study has 2 phases. Phase 1 will be an open-label study and Phase 2 will be an in-lab randomized controlled trial pilot study. This is phase 1 of the study.

Description

For phase 1, participants will attend up to 12 4-hour sessions using the dynamic standing desk. In addition to these sessions, there will be a clinical assessment at baseline and an outcome session (endpoint assessments). In total, there will be up to 14 sessions per participant. All sessions need to be completed within 6 weeks. At the baseline session, clinical measurements will be collected. These measures will be repeated in the outcome session.

Eligibility

Inclusion Criteria:

  • Diagnosis of Parkinson's Disease

Exclusion Criteria:

  • Inability to stand or walk without an assistive device
  • History of symptoms in stance that preclude safe and comfortable participation, such as dizziness and lightheadedness, orthostasis, severe symptomatic leg or back musculoskeletal pain, or medication side effects
  • Any other history of medical or psychiatric comorbidity, precluding safe participation in the project.
  • History of symptomatic cardiovascular or pulmonary disease
  • History of active rheumatic arthritis
  • History of stroke or other neurologic conditions with significant residual sensorimotor deficits
  • History of disabling chronic pain syndrome requiring narcotic analgesics
  • Evidence of dementia (Mini Mental State Exam (or Montreal Cognitive Assessment test) \<24 and significant impairment in activities of daily living)
  • Venous ulcerative stasis or severe varicosities.
  • Pregnancy as determined by urine pregnancy test prior to DXA procedure in women of childbearing potential.

Study details
    Parkinson Disease

NCT07543861

University of Michigan

13 May 2026

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FAQs

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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