Overview

The purpose of this study is to assess the feasibility and safety of ICG-guided intraoperative lymphography for detecting sentinel lymph nodes (SLN) in pediatric patients with solid tumors who require retroperitoneal lymph node dissection/sampling.

This trial is a single-site cross-sectional study. The injection of ICG directly into lymphatics draining the primary tumor will take place at the time of operation after the patient is under anesthesia.

Eligibility

Inclusion Criteria:

• Any pediatric patient (under the age of 18 years) being treated at the University of Rochester Medical Center, Department of Surgery.
• Diagnosed with pediatric solid tumor
• Scheduled to undergo lymph node sampling as part of their clinical management.

Exclusion Criteria:

• Subjects with a history of iodide allergies.
• Inability or unwillingness of research participant or parent/legal guardian to give written informed consent.
• Currently pregnant.
• Infants under 650 grams.
• Patients with extensive prior surgery at the primary site or nodal basin expected to affect the lymphatic drainage.