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Laparoscopic Versus Open Nephrectomy : Clinical Effectivness and Cost Analysis

Laparoscopic Versus Open Nephrectomy : Clinical Effectivness and Cost Analysis

Recruiting
1 years and older
All
Phase N/A

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Overview

To evaluate and compare clinical effectiveness (operative time, blood loss, hospital stay, complications and etc) and cost analysis' between laparoscopic nephrectomy and open nephrectomy .

Eligibility

Inclusion Criteria:

  • American Society of Anesthesiology score 1-3.
  • Indication for :
    • Simple total nephrectomy or hemi nephrectomy: benign chronic inflammatory non-functioning kidney
    • Partial nephrectomy: localized renal mass ≤7 cm suitable for nephron-sparing surgery.
    • Radical nephrectomy or Radical nephrouretrectomy with bladder cuff: localized renal tumor requiring complete nephrectomy without major vascular invasion.
  • Patient deemed fit for general anesthesia and surgery.
  • Patient provides written informed consent.

Exclusion Criteria:

  • emergency surgery, dialysis-dependent patients, planned hybrid procedures.
  • Patients with incomplete data
  • Patients with metastatic disease at presentation.
  • Prior extensive ipsilateral retroperitoneal surgery or severe adhesions precluding Laparoscopy.
  • Need for concomitant major procedures (eg, large bowel resection) at index operation.
  • Locally advanced tumor with obvious major vascular involvement requiring complex vascular reconstruction.
  • Uncorrected coagulopathy.
  • Pregnancy or Obese patient (BMI \> 40)
  • Inability to provide informed consent or comply with follow-up.

Study details
    Nonfunctioning Kidney
    Renal Cell Carcinoma (RCC)

NCT07461090

Menoufia University

13 May 2026

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