Overview
The goal of this observational study is to assess non-invasive tools' efficacy in predicting portal hypertension-related complications in individuals with advanced chronic liver disease. The main question it aims to answer are:
\- what are the cut-off values for non-invasive tests (NITs) (including LSM, SSM) that predict the presence and occurrence of hepatic decompensation in individuals with advanced chronic liver disease?
Participants will undergo regular study visits involving non-invasive tests (LSM, SSM) and assessments to monitor hepatic decompensation over the study period.
Eligibility
Inclusion Criteria:
- Age above 18years old
- Advanced chronic liver disease (defined as LSM ≥ 10kPa)
- Ability to provide informed consent
Exclusion Criteria:
- Transjugular intrahepatic portosystemic shunt
- previous liver transplantation
- Abnormality of the porto-mesenteric system (portal vein thrombosis, splenic vein thrombosis, splenectomy, portal cavernomatous transformation, porto-caval shunts)
- Hematological malignancy
