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Improving Postoperative Recovery: A Study of Multimodal Perineal Analgesia Protocol (MPAP) After Vaginal Surgery

Improving Postoperative Recovery: A Study of Multimodal Perineal Analgesia Protocol (MPAP) After Vaginal Surgery

Recruiting
18 years and older
Female
Phase 4

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Overview

The purpose of this research is to determine if using perineal ice packs, medicated witch-hazel pads (MAJOR® Medi-Pads), and topical benzocaine spray (Dermoplast®) helps reduce perineal pain after perineorrhaphy and/or posterior colporrhaphy surgery.

Eligibility

Inclusion Criteria:

  • Women ≥ 18 years of age
  • Undergoing perineorrhaphy and/or posterior colporrhaphy (rectocele repair/posterior repair) as part of their planned vaginal pelvic reconstructive surgery
  • Physically able to apply medicated witch-hazel pads (MAJOR® Medi-Pads) and administer topical benzocaine spray (Dermoplast®) to the perineal area
  • Able to understand and willing to provide informed consent

Exclusion Criteria:

  • Known allergy or hypersensitivity to any of the study products or components, including witch hazel, benzocaine, aloe, or other product ingredients
  • Minors
  • Presence of an indwelling catheter expected to remain in place for ≥7 days postoperatively
  • History of chronic pelvic pain syndromes that may confound postoperative pain assessment, including interstitial cystitis/bladder pain syndrome (IC/BPS), endometriosis, pudendal neuralgia, or vulvodynia
  • Chronic use (\> 3 weeks of continuous use) of opioid pain medication
  • Presence of vulvar dermatoses such as lichen sclerosus, lichen planus, or lichen simplex chronicus
  • Currently pregnant or breastfeeding
  • Anticipated inability to complete postoperative follow-up, including physical or cognitive limitations that would impede self-care or completion of study diaries
  • Inability or unwillingness to provide informed consent or comply with study procedures

Study details
    Perineal Injury
    Pain Vulva
    Perineum; Injury

NCT07401134

University of Miami

13 May 2026

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