Overview
The study aims to optimize individualized treatment of anti-infective drugs in osteoarticular infections by analyzing drug exposure in patients blood and/or tissues using population pharmacokinetics.
Eligibility
Inclusion Criteria:
- Diagnosis of knee osteoarthritis according to ACR knee osteoarthritis diagnostic criteria
- Being in stage 2 or 3 according to Kellgren-Lawrence radiological staging criteria
- having received an intra-articular injection in the knee within the past month
- To be 18 years of age or older
- Being a reader-writer
- Having read and signed the informed consent
Exclusion Criteria:
- History of major psychiatric illness
- Having malignant disease
- Having chronic infectious or other rheumatologic diseases
- Serious knee trauma or surgical operation in the last 6 months
- Having collagen tissue disease
- History of peripheral vascular disease or neuropathy
- Being in stage 4 according to Kellgren Lawrence radiologic staging criteria
- To have received a physiotherapy program for the relevant knee in the last 3 months


