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Community-based Approach to Lowering Stress Through Mindfulness

Community-based Approach to Lowering Stress Through Mindfulness

Recruiting
18 years and older
All
Phase N/A

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Overview

The goal of this clinical trial is to test a culturally adapted mindfulness-based stress reduction intervention in a community setting for African American adults with high blood pressure (hypertension) and depression. The main questions it aims to answer are:

  • Does participation in a culturally adapted mindfulness-based intervention improve depressive symptoms?
  • Does participation in a culturally adapted mindfulness-based intervention improve blood pressure control?
  • Is the intervention acceptable, appropriate, and feasible as delivered in a community setting?

Participants will:

  • Participate in an 8-week group-based mindfulness intervention (CALM-Chicago). During intervention sessions, participants will learn about mindfulness and stress management and complete mindfulness-based activities, such as guided deep breathing and meditation.
  • Complete surveys online
  • Have their blood pressure measured with a non-invasive blood pressure cuff
  • Attend 1 focus group (optional)

Eligibility

Inclusion Criteria:

  • ≥18 years old
  • Lives, works, or spends much of their time in the South Side of Chicago neighborhood
  • Self-reports diagnosis of hypertension or high blood pressure by a clinician
  • Endorses elevated depressive symptoms as Patient Health Questionnaire (PHQ)-9 scores ≥10
  • Not taking antidepressant medication or stable on antidepressant medication for ≥6 months as self-reported

Exclusion Criteria:

  • \<18 years old
  • Severe mental illness (e.g., bipolar disorder, psychosis)
  • Current suicidal ideation (PHQ-9 item 9) or recent (past 6 months) suicide attempt
  • Unable to provide informed consent or complete study activities in English

Study details
    Depression
    Hypertension

NCT06987799

Northwestern University

13 May 2026

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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