Overview
The goal of this clinical trial is to test a culturally adapted mindfulness-based stress reduction intervention in a community setting for African American adults with high blood pressure (hypertension) and depression. The main questions it aims to answer are:
- Does participation in a culturally adapted mindfulness-based intervention improve depressive symptoms?
- Does participation in a culturally adapted mindfulness-based intervention improve blood pressure control?
- Is the intervention acceptable, appropriate, and feasible as delivered in a community setting?
Participants will:
- Participate in an 8-week group-based mindfulness intervention (CALM-Chicago). During intervention sessions, participants will learn about mindfulness and stress management and complete mindfulness-based activities, such as guided deep breathing and meditation.
- Complete surveys online
- Have their blood pressure measured with a non-invasive blood pressure cuff
- Attend 1 focus group (optional)
Eligibility
Inclusion Criteria:
- ≥18 years old
- Lives, works, or spends much of their time in the South Side of Chicago neighborhood
- Self-reports diagnosis of hypertension or high blood pressure by a clinician
- Endorses elevated depressive symptoms as Patient Health Questionnaire (PHQ)-9 scores ≥10
- Not taking antidepressant medication or stable on antidepressant medication for ≥6 months as self-reported
Exclusion Criteria:
- \<18 years old
- Severe mental illness (e.g., bipolar disorder, psychosis)
- Current suicidal ideation (PHQ-9 item 9) or recent (past 6 months) suicide attempt
- Unable to provide informed consent or complete study activities in English


