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A Study to Evaluate ALN-4915 in Adult Healthy Volunteers

A Study to Evaluate ALN-4915 in Adult Healthy Volunteers

Recruiting
18-65 years
All
Phase 1
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Overview

The purpose of this study is to evaluate the safety, tolerability, pharmacodynamics (PD) and pharmacokinetics (PK) of ALN-4915.

Eligibility

Inclusion Criteria:

  • Is willing and able to complete all study assessments

Exclusion Criteria:

  • Has alanine aminotransferase (ALT) or aspartate aminotransferase (AST) \>upper limit of normal (ULN)
  • Has total bilirubin \>ULN
  • Has no history of invasive infection by an encapsulated organism
  • Has no known complement or immunologic deficiency

Study details
    Healthy Volunteers

NCT07535606

Alnylam Pharmaceuticals

13 May 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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