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Reducing Delirium After CABG Surgery With Early Activation and Sleep-Promoting Routines

Reducing Delirium After CABG Surgery With Early Activation and Sleep-Promoting Routines

Recruiting
21-99 years
All
Phase N/A

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Overview

The goal of this randomized-controlled trial (RCT) is to compare the effectiveness of the DREAMS-OT intervention with standard care in reducing post-Coronary Artery Bypass Graft (CABG) surgery delirium in patients undergoing CABG surgery.

The aims of the study are:

  1. To determine if early and intensive OT will lower the incidence of post-op delirium in CABG patients compared to standard are.
  2. To determine the cost effectiveness of the DREAMS-OT intervention.

The study team will compare intervention group and standard care group (control group) to see if there is a reduction in the incidence of delirium in patients 5 days post-CABG.

Eligibility

Inclusion Criteria:

  • Patients deemed medically suitable for elective CABG surgery
  • Patients aged 21 years and above
  • Patients who are English or Mandarin speaking.
  • Patients who are able to provide consent

Exclusion Criteria:

  • Patients who speak other languages are excluded due to the language requirements of certain outcome measures.
  • Patients with premorbid severe hearing impairment, severe cognitive impairment, progressive neurological disorders and psychological disorders will be excluded.
  • Patients with surgical complications resulting in profuse bleeding from any invasive sites, septic shock unresponsive to maximal treatment, and those who are moribund or have an expected mortality within 48 hours will be excluded.
  • Pregnant women will also be excluded from the study as well.
  • Patients who develop delirium before initiation of the treatment are also excluded from the study.

Study details
    Delirium
    Postoperative

NCT06107517

National University Hospital, Singapore

13 May 2026

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