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Impact of Glasses for Vision Problems on Cognitive Function in Rural Older Adults

Impact of Glasses for Vision Problems on Cognitive Function in Rural Older Adults

Recruiting
60-79 years
All
Phase N/A

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Overview

The aim of this project is to explore whether vision correction can effectively slow cognitive decline in older adults.

The primary question it seeks to answer is: Can providing free near and/or distance vision correction glasses to older adults with refractive errors or uncorrected vision, who have normal baseline cognition and hearing, reduce the rate of cognitive decline over 36 months in a cost-effective manner? Researchers will compare the rate of cognitive decline over 36 months between older adults who receive refractive correction and those who do not.

Eligibility

Inclusion Criteria:

  • Older adults who meet all of the following criteria will be eligible to participate in this study:
    • Registered as a rural resident (holding rural household registration);
    • Age from 60 to 79 years at the time of enumeration;
    • Resident in the household for \> = 3 months and planning to reside in the local area for the trial duration;
    • Distance vision impairment (VI, presenting visual acuity \[VA\] \< 6/18 in the better-seeing eye and improving to \> = 6/18 with spectacles) and/or near VI (presenting near vision \< N6 at 40 cm and improving to \> = N6 with spectacles);
    • Independent mobility with or without the support of a walking stick;
    • Chinese version of the Mini-Mental State Examination (C-MMSE) score above the following cut-offs (out of 30): \>17 for illiterate participants, \>20 for those with primary school education, \>22 for those with junior high school education, and \>23 for those with high school education or above.
    • Willingness to participate, to be randomized to either study group, and to adhere to the protocol

Exclusion Criteria:

  • Presence of glaucoma or visually significant cataract, or a history of surgical treatment for these or other major ocular conditions;
  • Consistent use of prescription spectacles and/or hearing aids;
  • Serious medical illness likely to result in loss to follow-up. Those less severely affected by conditions such as hypertension and/or diabetes will be eligible;
  • Failure on the whispered voice hearing screening test in the better ear (unable to repeat \> = 3 out of 6 words whispered from behind the participant at a distance of 50 cm);

Study details
    Cognition Disorders

NCT06836440

Yuju Wu

14 May 2026

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