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Effect of Adding Ultrasound Guided IPACK Block to Adductor Canal Block for Postoperative Pain in Knee Tumor Excision

Effect of Adding Ultrasound Guided IPACK Block to Adductor Canal Block for Postoperative Pain in Knee Tumor Excision

Recruiting
18-65 years
All
Phase N/A

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Overview

the aim of this study is to determine the analgesic effect of iPACK in combination to ACB after the excision of tumors around the Knee regarding the following:

  • Time to the 1st rescue analgesia.
  • Postoperative morphine consumption.
  • Postoperative visual analogue scale (VAS). This study will include patients, aged 18 to 65 years, belonging to the American Society of Anesthesiologists (ASA) physical status II to IV , undergoing excision of tumors around the knee under spinal anesthesia.

Patients will be randomly allocated Group iPACK plus Adductor canal block (ACB) : patients will receive ACB plus iPACK block.

• Control group : patients will not receive any block but will take morphine 3mg bolus at VAS more than 4 and regular NSAIDS and paracetamol iv.

Description

Immediate alleviation of postoperative pain after knee surgeries is critical for patients' postoperative recovery. Ineffective pain management may result in an extended hospital stay and rehabilitation period, as well as the development of chronic pain Non-opioid analgesics are insufficient to alleviate the pain that is intended to be relieved.

Although using Opioids have concerns regarding their potential side effects, which encompass nausea, vomiting, respiratory depression, and addiction Multimodal analgesia, which may include preemptive analgesia, neuraxial blockade, peripheral nerve block, and narcotic and non-narcotic analgesics, is an optimal approach for the management of acute pain following knee surgeries Adductor canal block (ACB) is an interfascial plane infiltration of local anesthetic used to block a portion of the saphenous nerve, which originates in the adductor canal, as well as the obturator nerve ACB combined with an iPACK block results in significantly better postoperative visual analog scale (VAS) scores, knee ranges of motion, as well as ambulation distances compared with ACB alone

Eligibility

Inclusion Criteria:

  • Stated willingness to comply with all study procedures and availability for the duration of the study
  • American Society of Anesthesiologists (ASA) physical status II-IV.
  • Patients undergoing excision of tumors around the knee under spinal anesthesia

Exclusion Criteria:

  • Patient refusal.
  • Neuromuscular disorders
  • Allergy to local anesthetics
  • Previous history of knee surgery
  • Patients with a prior knee infection
  • Contraindications to spinal anesthesia as coagulopathies and severe aortic stenosis.

Study details
    Cancer Pain

NCT07382297

National Cancer Institute, Egypt

13 May 2026

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