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AI-Guided Left Bundle Branch Area Pacing

AI-Guided Left Bundle Branch Area Pacing

Recruiting
18 years and older
All
Phase N/A
  • Technical (Original)
  • Simplified (AI rewritten)

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Overview

The purpose of this study is to compare the effectiveness of AI-guided LBBAP versus conventional LBBAP (not AI-guided) in improving CRT response rates and clinical outcomes.

Eligibility

Inclusion Criteria

  • Age: 18 years or older.
  • Left Ventricular Ejection Fraction (LVEF): \<50% within 6 months prior to enrollment.
  • QRS Duration: Resting QRS duration ≥ 130 ms on ECG OR anticipated right ventricular pacing \> 40% OR device in place with right ventricular pacing \> 40% within 6 months prior to enrollment.
  • Medical Therapy: Optimized on guideline-directed medical therapy for heart failure.
  • AI-ECG probability of low LVEF: \>0.5

Exclusion Criteria

  • Age less than 18 years old
  • Inability to follow-up
  • Pregnancy

Study details
    Heart Failure

NCT07206602

Mayo Clinic

26 February 2026

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